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22% OFF FLASH SALE! 24 hours only! Save 22% off all orders $99+ SITEWIDE! Use code: SINGLESDAY24
To redeem at checkout, enter code SINGLESDAY24 in the offer code box with any order $99+ to receive 22% off your purchase. Available for MSRP only. Not valid on Subscribe + Save items. Valid thru 11/11/24 at 11:59 PM MT.
Free mini gift options! Choose your free gift with any $85+ Order. Use code: NOV24
To redeem at checkout, enter code NOV24 in the offer code box to receive a FREE mini C-Shield Anti-Pollution Drops or mini HA-Revive Hyaluronic Drops with any $85+ order. While supplies last.
All promotions available for MSRP only. Not valid on Subscribe and Save items. Not valid on prior purchases. Offers may not be combined with any other sale, promotion, discount, code, coupon and/or offer.

Bio-Renew EGF Cream

Fill: 1.7 fl. oz.
$178.00
A transformative, age-defying face cream powered by vegan EGF, bio-recovery peptides, and phyto-retinol, for next-level firming, smoothing, and hydration.
Award Winning
Clinicals
Vegan
Cruelty Free
Paraben Free
Phthalate Free
Sulfate Free

Restore skin's strength and smooth signs of aging with this next-level, rich, reparative Bio-Renew EGF Cream. Formulated in partnership with leading board-certified dermatologist Dr. Dendy Engelman, this new-generation treatment moisturizer is clinically proven to reduce fine lines and wrinkles for a more youthful appearance, hydrating, smoothing, and firming skin in 30 days or less.

Powered by an age-defying, restorative blend of vegan EGF (epidermal growth factor) and bio-recovery peptides, it revitalizes and renews both on skin's surface and deep within. Strengthening skin's moisture barrier and locking in hydration, phyto-retinol complex—a plant-based alternative to retinol, smooths and firms the appearance of fine lines and wrinkles, for perfectly plumped, hydrated skin and rejuvenated radiance.

Suitable for all skin types—especially those with aging concerns.

Key Benefits:

  • Repairing: A dual-action reparative complex restores and rejuvenates from within, supporting cellular renewal for a more radiant complexion.
  • Strengthening: Repairs and fortifies skin's barrier for revitalized hydration.
  • Firming: Smooths and plumps skin, reducing the appearance of fine lines and wrinkles.

Key Ingredients:

  • 1% Epidermal Growth Factor: Vegan EGF is the ultimate reparative ingredient in skincare. It’s a protein that occurs naturally in human skin and provides healing benefits. Glo only uses vegan—never animal derived, EGF in its formulations, which mimics the human protein to boost collagen and elastin production.
  • Phyto-Retinol Complex: A plant-based alternative to retinol that’s equally as effective in firming, smoothing, and reducing the appearance of fine lines and wrinkles, without causing sensitivities or irritation.
  • Bio-Recovery Peptides: Powerful peptides help repair and firm skin from within.
Aqua/Water/Eau, Glycerin, Cetearyl Alcohol, Cetyl Alcohol, Glyceryl Stearate, Shea Butter Ethyl Esters, Cystoseira Amentacea/Caespitosa/Branchycarpa Extract, Vaccinium Macrocarpon (Cranberry) Fruit Extract, Acacia Senegal Gum, Linoleic Acid, Sodium Acrylates Copolymer, Bixa Orellana Seed Extract, Butyrospermum Parkii (Shea) Butter, Kalanchoe Pinnata Leaf Extract, Mangifera Indica (Mango) Seed Butter, Bakuchiol, Lecithin, Linolenic Acid, Laminaria Saccharina Extract, Butyrospermum Parkii (Shea) Oil, Kappaphycus Alvarezii Extract, Gigartina Stellata Extract, Phospholipids, Padina Pavonica Thallus Extract, Lipase, Butylene Glycol, Disodium EDTA, Olea Europaea (Olive) Fruit Oil, Propanediol, Corallina Officinalis Extract, Protease, Arginine, Citric Acid, Tocopherol, Crocus Chrysanthus Bulb Extract, Hyaluronic Acid, Silanetriol, sh-Oligopeptide-1, Acetyl Hexapeptide-49

Apply an even layer to face and neck and massage lightly into skin.

Can be used AM and/or PM, depending on your skin’s needs. Apply moisturizer after cleanser, toner, serum, and then eye cream. Always follow with SPF in the morning.

Pairs With:

  • Bio-Renew EGF Drops for the ultimate anti-aging duo. Apply Bio-Renew EGF Drops first and seal them in with Bio-Renew EGF Cream.
  • The perfect age-defying eye treatment, Phyto-Active Eye Serum firms, hydrates, and helps reduce the appearance of fine lines and wrinkles.
  • As a weekly treatment, Phyto-Active Firming Mask is a luxurious and nourishing mask infused with platinum extract to restore, firm, and brighten skin.
What's the difference between Bio-Renew EGF Cream and Bio-Renew EGF Drops?
Bio-Renew EGF Drops are an EGF serum, while Bio-Renew EGF Cream is an EGF moisturizer. Both feature vegan epidermal growth factor, an innovative reparative ingredient that helps repair skin’s barrier and boost collagen and elastin production for improved elasticity and radiance. A serum is a more concentrated and targeted delivery method for active ingredients, while a moisturizer focuses on conditioning and cushioning skin. Both EGF skincare products can be used together for even better results.
Is Bio-Renew EGF Cream recommended to use after professional treatments?
Yes, Bio-Renew EGF Cream is the perfect post-treatment moisturizer to help restore and repair skin. It can also be used as part of your daily anti-aging skincare regimen too.
Can I try samples of this cream?
We have a handy discovery size set, Bio-Renew EGF Repair Duo, which contains mini sizes of both Bio-Renew EGF Cream plus Bio-Renew EGF Drops, and is perfect for trial or travel. We also have samples available to purchase here.
What is EGF?
Epidermal growth factor (EGF) is the ultimate reparative ingredient in skincare. The scientists who discovered it 30 years ago won a Nobel Prize for their work using EGF in medicine for burn patients, making it one of the most innovative ingredients in the skincare world right now. It’s a protein that occurs naturally in human skin and provides healing benefits. Glo only uses vegan—never animal derived, EGF in its formulations, which mimics the human protein to boost collagen and elastin production. Our Bio-Renew EGF Cream is perfect for those seeking EGF skincare that is clinically proven to deliver anti-aging results. With continued use, this cream visibly reduces fine lines, wrinkles, and signs of aging, making it one of the top-rated EGF creams available. Learn more about Epidermal Growth Factor in Skincare
Does EGF tighten skin?
EGF signals cells to boost collagen and elastin production, to improve and maintain elasticity and clarity which can create a firmed, lifted effect.

Restore skin's strength and smooth signs of aging with this next-level, rich, reparative Bio-Renew EGF Cream. Formulated in partnership with leading board-certified dermatologist Dr. Dendy Engelman, this new-generation treatment moisturizer is clinically proven to reduce fine lines and wrinkles for a more youthful appearance, hydrating, smoothing, and firming skin in 30 days or less.

Powered by an age-defying, restorative blend of vegan EGF (epidermal growth factor) and bio-recovery peptides, it revitalizes and renews both on skin's surface and deep within. Strengthening skin's moisture barrier and locking in hydration, phyto-retinol complex—a plant-based alternative to retinol, smooths and firms the appearance of fine lines and wrinkles, for perfectly plumped, hydrated skin and rejuvenated radiance.

Suitable for all skin types—especially those with aging concerns.

Key Benefits:

  • Repairing: A dual-action reparative complex restores and rejuvenates from within, supporting cellular renewal for a more radiant complexion.
  • Strengthening: Repairs and fortifies skin's barrier for revitalized hydration.
  • Firming: Smooths and plumps skin, reducing the appearance of fine lines and wrinkles.

Key Ingredients:

  • 1% Epidermal Growth Factor: Vegan EGF is the ultimate reparative ingredient in skincare. It’s a protein that occurs naturally in human skin and provides healing benefits. Glo only uses vegan—never animal derived, EGF in its formulations, which mimics the human protein to boost collagen and elastin production.
  • Phyto-Retinol Complex: A plant-based alternative to retinol that’s equally as effective in firming, smoothing, and reducing the appearance of fine lines and wrinkles, without causing sensitivities or irritation.
  • Bio-Recovery Peptides: Powerful peptides help repair and firm skin from within.
Aqua/Water/Eau, Glycerin, Cetearyl Alcohol, Cetyl Alcohol, Glyceryl Stearate, Shea Butter Ethyl Esters, Cystoseira Amentacea/Caespitosa/Branchycarpa Extract, Vaccinium Macrocarpon (Cranberry) Fruit Extract, Acacia Senegal Gum, Linoleic Acid, Sodium Acrylates Copolymer, Bixa Orellana Seed Extract, Butyrospermum Parkii (Shea) Butter, Kalanchoe Pinnata Leaf Extract, Mangifera Indica (Mango) Seed Butter, Bakuchiol, Lecithin, Linolenic Acid, Laminaria Saccharina Extract, Butyrospermum Parkii (Shea) Oil, Kappaphycus Alvarezii Extract, Gigartina Stellata Extract, Phospholipids, Padina Pavonica Thallus Extract, Lipase, Butylene Glycol, Disodium EDTA, Olea Europaea (Olive) Fruit Oil, Propanediol, Corallina Officinalis Extract, Protease, Arginine, Citric Acid, Tocopherol, Crocus Chrysanthus Bulb Extract, Hyaluronic Acid, Silanetriol, sh-Oligopeptide-1, Acetyl Hexapeptide-49

Apply an even layer to face and neck and massage lightly into skin.

Can be used AM and/or PM, depending on your skin’s needs. Apply moisturizer after cleanser, toner, serum, and then eye cream. Always follow with SPF in the morning.

Pairs With:

  • Bio-Renew EGF Drops for the ultimate anti-aging duo. Apply Bio-Renew EGF Drops first and seal them in with Bio-Renew EGF Cream.
  • The perfect age-defying eye treatment, Phyto-Active Eye Serum firms, hydrates, and helps reduce the appearance of fine lines and wrinkles.
  • As a weekly treatment, Phyto-Active Firming Mask is a luxurious and nourishing mask infused with platinum extract to restore, firm, and brighten skin.
What's the difference between Bio-Renew EGF Cream and Bio-Renew EGF Drops?
Bio-Renew EGF Drops are an EGF serum, while Bio-Renew EGF Cream is an EGF moisturizer. Both feature vegan epidermal growth factor, an innovative reparative ingredient that helps repair skin’s barrier and boost collagen and elastin production for improved elasticity and radiance. A serum is a more concentrated and targeted delivery method for active ingredients, while a moisturizer focuses on conditioning and cushioning skin. Both EGF skincare products can be used together for even better results.
Is Bio-Renew EGF Cream recommended to use after professional treatments?
Yes, Bio-Renew EGF Cream is the perfect post-treatment moisturizer to help restore and repair skin. It can also be used as part of your daily anti-aging skincare regimen too.
Can I try samples of this cream?
We have a handy discovery size set, Bio-Renew EGF Repair Duo, which contains mini sizes of both Bio-Renew EGF Cream plus Bio-Renew EGF Drops, and is perfect for trial or travel. We also have samples available to purchase here.
What is EGF?
Epidermal growth factor (EGF) is the ultimate reparative ingredient in skincare. The scientists who discovered it 30 years ago won a Nobel Prize for their work using EGF in medicine for burn patients, making it one of the most innovative ingredients in the skincare world right now. It’s a protein that occurs naturally in human skin and provides healing benefits. Glo only uses vegan—never animal derived, EGF in its formulations, which mimics the human protein to boost collagen and elastin production. Our Bio-Renew EGF Cream is perfect for those seeking EGF skincare that is clinically proven to deliver anti-aging results. With continued use, this cream visibly reduces fine lines, wrinkles, and signs of aging, making it one of the top-rated EGF creams available. Learn more about Epidermal Growth Factor in Skincare
Does EGF tighten skin?
EGF signals cells to boost collagen and elastin production, to improve and maintain elasticity and clarity which can create a firmed, lifted effect.

Clinically Proven Results

Clean + Clinical Results At Home
Clinically proven to reduce fine lines and wrinkles, improve skin’s brightness, balance skin tone, hydrate skin, and increase firmness
92% saw smoother skin
92% said there was improved appearance of texture and smoothness after 1 month of use
96% saw more hydrated skin
96% said skin feels deeply hydrated and softer after 1 month of use
92% saw healthier skin
92% said skin looks healthy, plumped, and replenished after 1 month of use
Significant reduction in wrinkles
Scientifically proven to reduce wrinkles + fine lines by a statistically significant amount within 30 days
Complete Your Routine
Phyto-Active Enzyme Cream Cleanser
Hydra-Bright Pro 5 Liquid Exfoliant
Phyto-Active Eye Serum
Bio-Renew EGF Drops
Bio-Renew EGF Cell Repairing Facial
Phyto-Active Firming Mask
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